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Supplement reference

103 items with A/B/C evidence levels. A level reflects the type of research, not popularity: A means systematic reviews and meta-analyses, B individual good randomised trials, C scarce data. Where no studies exist for a goal, the page says so.

Reviews

Overrated · 37

  • 'Testosterone boosters' (ZMA, tribulus and others) B They do not increase testosterone in healthy men
  • Arginine C Works poorly orally; the effect is weaker than that of citrulline
  • Astaxanthin C The data are few and point in different directions; there is no convincing effect
  • Boron C The data on testosterone and strength are weak and contradictory; the effect is not proven
  • Garcinia cambogia C The effect on weight is not confirmed; in meta-analyses there is no difference from placebo
  • Weight gainer B It is maltodextrin and sugar at the price of protein; ordinary food gives the same
  • Glutamine B Gives almost nothing to healthy athletes: neither growth nor immunity
  • Glucosamine and chondroitin B In knee pain the effect is small and borderline significant; it does not restore cartilage
  • Glucomannan C A soluble fiber with a small effect; the evidence is weak
  • Green coffee (chlorogenic acid) B Meta-analysis: about 1 kg over 8–12 weeks; the effect is small and inconsistent
  • Yohimbine C Dangerous: panic attacks, hypertension, prohibited in sport. Data are scarce
  • Raspberry ketone C There is no effect in humans; the data are limited to experiments on cells and rodents
  • Ketone esters B According to recent data, they worsen endurance rather than improve it
  • Conjugated linoleic acid (CLA) A Meta-analysis: about 0.1 kg of fat per week at 3.2 g/day — in practice almost imperceptible
  • Coenzyme Q10 (ubiquinone) C Raises the blood concentration, improves performance inconsistently
  • Creatine HCl C No proven advantages over monohydrate; overpayment
  • Laxogenin C A steroidal saponin from Smilax: there are no controlled data in humans
  • Maca C In a pilot RCT the result did not differ from placebo; data are scarce
  • Methylsulfonylmethane (MSM) C A single RCT showed no protection of muscle after exercise; data are scarce
  • Deer antler velvet C The only RCT did not confirm a gain in strength or aerobic capacity
  • Synephrine C No benefit has been proven; there is a risk of cardiotoxicity and a rise in blood pressure
  • Theacrine C The effect is NOT confirmed: a 2025 study revealed no improvement
  • Turkesterone C There are no controlled studies in humans; the popularity is not supported by data
  • Phenibut (β-phenyl-GABA) C A prescription drug with a high risk of dependence; it is not a supplement
  • Forskolin (Coleus forskohlii) C Small studies of questionable quality; there is no independent confirmation of the effect
  • Sodium phosphate C Results are contradictory: one study showed an effect, the second did not
  • Chitosan B Meta-analysis: about 1 kg over several months — practically insignificant
  • Chromium C Does not help fat loss or body composition in healthy people; data are scarce
  • Shilajit (mumijo) C The only study is open-label, without a comparison group: the effect is not proven
  • Ecdysterone C One small RCT showed muscle gain, but the effect is weak and has not been reproduced
  • Green tea extract (EGCG) C The effect is small; there is a risk of rare but severe liver injury
  • Ephedra and ephedrine A A moderate weight reduction, but a serious risk to the heart
  • Apple cider vinegar C The claimed effects on weight are not reproduced; the data of the studies raise serious doubts
  • BCAA (branched-chain amino acids) B A weak effect: a complete protein does the same better and cheaper
  • D-ribose C The study showed no effect; the benefit for athletes is not confirmed
  • HMB (beta-hydroxy-beta-methylbutyrate) B Almost useless for trained individuals: the evidence is contradictory
  • L-carnitine B Does not burn fat: the average effect is about 1–1.2 kg and is clinically insignificant

For the goal · 20

  • Alpha-glycerylphosphorylcholine C One small study; the effect is not confirmed, data are scarce
  • Beta-alanine A Helps during exercise lasting 0.5–10 minutes; does not affect sprints shorter than 30 seconds
  • Betaine B A small and unstable effect on strength; it changes body composition little
  • Sodium bicarbonate (baking soda) A Works for exercise lasting 1–10 minutes; the price is gastrointestinal upset
  • Glycerol for hyperhydration B Retains water, but the gain in performance is unstable
  • Cluster dextrin C The same as HBCD: leaves the stomach faster, but no gain in performance has been shown
  • Cordyceps C Contradictory data: one study showed benefit, another showed absence of effect
  • Caffeine A A working supplement: endurance +2–4%, strength moderately
  • Caffeine in chewing gum A Fast and reliable action: the effect begins already on chewing
  • Creatine nitrate C There are very few data; no advantages over monohydrate have been shown
  • Nitrates (beetroot juice) B Moderately improves endurance; the response varies considerably between individuals
  • Ornithine alpha-ketoglutarate C Insufficient data: there are no studies of this particular form
  • Fenugreek C Four RCTs out of six showed an effect, but the samples are small and the quality is low
  • Oral ATP C A meta-analysis of small studies; the quality of the data is low, the effect is unclear
  • Taurine B The data are weak and heterogeneous; benefit is possible at high training volumes
  • Tyrosine B Works under stress and sleep deprivation; in a calm state there is no effect
  • Carbohydrate-electrolyte drink A The main working tool for exercise longer than 90 minutes
  • Sodium citrate B Alkalinizing supplement: a moderate effect on endurance, studied less thoroughly than bicarbonate
  • Citrulline malate B A modest effect: an increase in the number of repetitions is possible, the data are heterogeneous
  • HBCD (highly branched cyclic dextrin) C Studied only for the rate of gastric emptying; no gain in performance has been shown

Health · 20

  • Vitamin A (retinol, carotenoids) C There are no sports data; excess is dangerous — chronic overdose is toxic
  • Vitamin B12 (cobalamin) B Critical in a vegan diet; in athletes with adequate intake there is no effect
  • Vitamin C (ascorbic acid) B Corrects the deficiency but gives no gain in endurance; high doses interfere with adaptation
  • Vitamin D B Useful only in deficiency: it does not increase strength in those with adequate intake
  • Vitamin E (tocopherols, tocotrienols) C An antioxidant without a proven effect on performance; the effect is not confirmed
  • Vitamin K2 (menaquinones) C Potentially beneficial for bones and blood vessels, but sports outcomes have not been studied
  • B-group vitamins (complex) C Important in deficiency, they do not improve performance in athletes with adequate intake
  • Iron B Helps in deficiency; without deficiency it is useless and harmful
  • Ginseng (Panax ginseng) C Systematic review: did not reduce markers of muscle damage after resistance exercise
  • Iodine C Needed by the thyroid, but without deficiency the supplements are more likely harmful than useful
  • Potassium C Does not treat cramps with potassium supplements; benefit only in dietary deficiency
  • Magnesium C Needed in deficiency; it does not improve performance in those with adequate intake
  • Multivitamins C Insurance against deficiency, but not a way to improve performance
  • Omega-3 (EPA and DHA) B There is a health benefit, the gain in performance is weak
  • Probiotics B Data are limited: a moderate reduction in the risk of respiratory and gastrointestinal disorders at high traini…
  • Rhodiola rosea B The most consistently studied adaptogen, but the study results diverge
  • Selenium C Deficiency is harmful, but supplements above the requirement do not improve performance and are toxic
  • Tryptophan C Does not increase performance; the sports data are old and weak
  • Folate (vitamin B9, folic acid) C Corrects deficiency and supports erythropoiesis, but does not improve performance
  • Zinc B Deficiency reduces strength and testosterone; with adequate status there is no effect

Base · 14

  • Beef protein B In a meta-analysis of seven RCTs it was not inferior to whey in lean mass and leg strength
  • Pea protein B Was not inferior to whey in a 12-week RCT; less leucine per gram than in milk proteins
  • Casein protein B A slow protein; an advantage over whey is not proven
  • Calcium B Needed for bones, but supplements above the diet do not strengthen bones
  • Creatine monohydrate A The most studied supplement: a consistent moderate improvement in strength and muscle gain
  • Leucine B A separate supplement confers no advantage when protein is adequate
  • Maltodextrin B A cheap source of carbohydrate for prolonged work; produced no effect in resistance training
  • Sodium and electrolytes A For exercise longer than 2 hours, sodium with water protects against hyponatremia
  • Essential amino acids (EAA) B Theoretically better than BCAA, but not better than a complete protein
  • Plant protein blends B Blends of pea and rice are close to whey; single-component ones are weaker
  • Rice protein C A hypoallergenic plant protein, but there are few direct comparative studies
  • Soy protein B A complete protein: in a meta-analysis of nine studies it was not inferior to animal proteins
  • Whey protein A Tops up daily protein; the source of protein matters less than its total amount
  • Egg protein C The amino acid profile is reference-grade, but there are almost no supporting studies of the supplement

Recovery · 12

  • Ashwagandha B A modest effect on strength; the studies are small and heterogeneous
  • Valerian B One quality RCT showed improvement in sleep; there are no direct data on muscle and strength
  • Cherry juice (tart cherry) B Moderately reduces pain and markers of damage after exercise
  • Glycine C There are no data on sports performance; it has been studied mainly as a sleep aid
  • Sleep supplements (melatonin, glycine, magnesium) C Sleep is critical, but the evidence of benefit of supplements for performance is weak
  • Cannabidiol (CBD) B The effect on sports performance has not been shown; the data on recovery are preliminary
  • Collagen peptides B A small effect on tendon pain; it does not change the structure
  • Curcumin A Reduces creatine kinase and soreness after exercise; the effect is moderate
  • Lemon balm (Melissa officinalis) C A mild sedative; the effect on recovery and performance is not proven
  • Colostrum C There are data on recovery and immunity, but the doses and effects are inconsistent
  • Phosphatidylserine C A single study of cortisol reduction; the effect is not proven
  • L-theanine B Not ergogenic by itself; with caffeine it improves attention and reduces nervousness

How to use

Every page is a review of one item: mechanism, dosing by goal, confirmed effects, limits and a list of sources. Goal filters, comparisons and a calculation from your own data live in the app.