'Testosterone boosters' (ZMA, tribulus and others) B
They do not increase testosterone in healthy men
Citable fact
«'Testosterone boosters' (ZMA, tribulus and others)» — evidence level B. Dosage: Doses are stated on the packaging, but with normal nutrition there is no point: the supplement gives no gain in testosterone, strength or mass. Zinc 15–30 mg and magnesium as such are a matter of correcting deficiency. Source: PMID 37697053, permanent link to the source in the list below.
How it works
Zinc and magnesium participate in the synthesis of steroid hormones, but only in the presence of an initial deficiency. Tribulus terrestris and other plant components do not demonstrate a mechanism for raising testosterone in healthy people.
Dosage and intake
Doses are stated on the packaging, but with normal nutrition there is no point: the supplement gives no gain in testosterone, strength or mass. Zinc 15–30 mg and magnesium as such are a matter of correcting deficiency.
Before bed in most products; this does not affect the effect, because there is no effect itself.
Forms
ZMA (zinc, magnesium, vitamin B6), Tribulus terrestris, D-aspartic acid and mixes have been studied. Isolated positive results are not reproduced; data on most “boosters” are absent.
What is confirmed
- Systematic review: there is no convincing evidence of an increase in total testosterone in healthy men
- Tribulus did not raise testosterone or improve strength and body composition in RCTs
- ZMA may help with an initial zinc or magnesium deficiency — but that is a task of nutritional support, not of “boosting”
- No effect on mass and strength gains has been shown
Adverse effects and limitations
- A waste of money instead of sleep, nutrition and training
- High doses of zinc cause nausea and impair copper uptake
- Magnesium in large doses causes diarrhea
- Some products contain undeclared hormonal impurities
Interactions
- Zinc reduces the absorption of tetracyclines, fluoroquinolones and copper
- Vitamin B6 in large doses with long-term use causes neuropathy
Who must not use it
- Under 18 years: Not recommended: a potential effect on the hormonal system during growth.
- Pregnancy and lactation: Not used.
- confirmed zinc deficiency
- use of drugs that bind to zinc
Sources
- Do "testosterone boosters" really increase serum total testosterone? A systematic review · Morgado A, Tsampoukas G, Sokolakis I · International journal of impotence research, 2024 · PMID 37697053
- Low-fat diets and testosterone in men: Systematic review and meta-analysis of intervention studies · Whittaker J, Wu K · The Journal of steroid biochemistry and molecular biology, 2021 · PMID 33741447
- Position of the Academy of Nutrition and Dietetics, Dietitians of Canada, and the American College of Sports Medicine: Nutrition and Athletic Performance · Thomas DT, Erdman KA, Burke LM · Journal of the Academy of Nutrition and Dietetics, 2016 · PMID 26920240
- Adulteration of Sports Supplements with Anabolic Steroids-From Innocent Athlete to Vicious Cheater · Puscasiu D, Flangea C, Vlad D · Nutrients, 2025 · PMID 41097223
- Essential Features of Third-Party Certification Programs for Dietary Supplements: A Consensus Statement · Eichner AK, Coyles J, Fedoruk M · Current sports medicine reports, 2019 · PMID 31082891
See also
Open in the app
This page holds reference data with links to studies. In the app you can calculate calories and macros for your goal, build a personal supplement stack and review weekly training volume.