Deer antler velvet C

«Deer antler velvet» — evidence level C. Dosage: In an RCT — 1.5 g per day of antler extract or powder for 10 weeks. No independently confirmed effective dose exists. Source: PMID 14669926, permanent link to the source in the list below.

A mixture of proteins, collagen, minerals and growth factors, including IGF-1, in the raw material. It was assumed that IGF-1 would enhance the anabolic response and erythropoiesis, but when taken orally it is destroyed in the GI tract: in the study, levels of IGF-1, testosterone and erythropoietin did not change.

Antler extract (aqueous or alcoholic) and powder. Composition varies widely between products; there is no standardization.

• 2003 RCT: the gain in 6RM strength was the same in all groups; the authors themselves called the greater increase in isokinetic strength and endurance in the powder group a possible type I error
• There were no changes in testosterone, IGF-1, erythropoietin, red cell mass or VO2max in any group
• There is no independent reproduction of the strength and body composition results

• Antler products are a known source of contamination with IGF-1 and other hormonal substances; the claimed “natural” origin does not guarantee the absence of active doses of hormones
• Cases of prohibited anabolic steroids and stimulants being found in such products have been described
• Allergic reactions and GI reactions are possible
• Lack of standardization: different batches contain different amounts of components

• A theoretical effect on glucose levels and hormonal status; caution in endocrine diseases
• The combination with other hormonal boosters has not been studied

• Under 18 years: Contraindicated: hormonal action and contamination risk are unacceptable in childhood and adolescence.
• Pregnancy and lactation: Contraindicated in pregnancy and lactation.
• allergy to product components
• endocrine diseases
• history of cancer
• adolescence

• The effects of deer antler velvet extract or powder supplementation on aerobic power, erythropoiesis, and muscular strength and endurance characteristics · Sleivert G, Burke V, Palmer C · International journal of sport nutrition and exercise metabolism, 2003 · PMID 14669926
• Current Evidence to Propose Different Food Supplements for Weight Loss: A Comprehensive Review · Watanabe M, Risi R, Masi D · Nutrients, 2020 · PMID 32962190

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