Raspberry ketone C

«Raspberry ketone» — evidence level C. Dosage: Labels state 100–500 mg per day. There are practically no controlled human studies assessing body composition, and the effective dose is unknown. Source: PMID 34913499, permanent link to the source in the list below.

In structure it resembles capsaicin and synephrine. In cell and animal models it increases lipolysis and fatty acid oxidation, but in humans it is absorbed and metabolized quickly, so a systemic effect is hard to expect.

Powder in fat-burner complexes; almost always part of mixes where the effect cannot be attributed to it specifically.

• A 2022 review describes metabolic activity almost exclusively from preclinical data
• The doses at which the effect was observed in rodents would be hard for humans to tolerate: extrapolation does not work
• No clinically significant reduction in fat mass in humans has been obtained in controlled studies

• Tachycardia, increased blood pressure, tremor and insomnia are possible, especially in complexes with stimulants
• The safety of long-term use has not been studied
• A small dose in the product is useless, a large one has not been studied

• The combination with caffeine, synephrine and other stimulants increases cardiac load
• Caution in hypertension and cardiac arrhythmias

• Under 18 years: Not recommended.
• Pregnancy and lactation: Not recommended: there are no safety data.
• hypertension
• arrhythmias
• cardiovascular diseases
• anxiety disorders

• Potential metabolic activities of raspberry ketone · Li X, Wei T, Wu M · Journal of food biochemistry, 2022 · PMID 34913499
• Current Evidence to Propose Different Food Supplements for Weight Loss: A Comprehensive Review · Watanabe M, Risi R, Masi D · Nutrients, 2020 · PMID 32962190

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